Daptomycin for line-related Leuconostoc bacteraemia
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چکیده
منابع مشابه
Daptomycin, Methicillin Resistant Staphylococcus hominis Catheter-Related Bacteraemia in a Hemodialysis Patient
We report a case of a haemodialysis patient that presented a catheter-related bacteraemia caused by a Coagulase negative Staphylococcus. With the utilization of molecular biology techniques the bacterial isolate recovered from catheter was surprisingly identified as S. hominis by sequencing of the 16S ribosomal gene. The S. hominis isolate, which is not often associated with infections in dialy...
متن کاملDaptomycin for endocarditis and/or bacteraemia: a systematic review of the experimental and clinical evidence.
BACKGROUND Endocarditis and bacteraemia are devastating infections with high mortality. Gram-positive cocci are the most commonly isolated pathogens. In an era of multidrug-resistant pathogens, the evaluation of new treatment options is important. Daptomycin is a cyclic lipopeptide that is active against most of these pathogens. Furthermore, it is a bactericidal antibiotic, a factor that is fre...
متن کاملEmergence of resistance to daptomycin in a cohort of patients with methicillin-resistant Staphylococcus aureus persistent bacteraemia treated with daptomycin.
4 Theoretically estimated AUC 24 /MIC ratios against VRE susceptible to linezolid, according to the EUCAST clinical breakpoint (MIC¼ 4 mg/L), 1 were in the recommended range for the effective treatment of severe infections with linezolid (AUC 24 /MIC ratio of 80 –120) 6 in both cases (.93.76 and .250.96, respectively). In addition , biliary trough levels (C min) of linezolid were above the EUCA...
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CASEREPORT A 48-year-old female patient with a six-yearhistory ofnon-secretory multiple myeloma presented to hospital in September 2001 having felt generally unwell for the preceding two weeks. She lived in an urban area and had limited mobility. She described fevers withrigors on anumberofoccasions particularly associated with flushing of a Hickman line, which had been in situ since July 1999....
متن کاملMultiple pathways of cross-resistance to glycopeptides and daptomycin in persistent MRSA bacteraemia.
BACKGROUND The development of non-susceptibility to glycopeptides and daptomycin in MRSA during persistent bacteraemia has become a significant therapeutic challenge. However, the in vivo evolution and mechanism of the dual resistance have remained incompletely understood. METHODS A series of MRSA blood isolates with incremental non-susceptibility to glycopeptides and daptomycin were consecut...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2001
ISSN: 1460-2091
DOI: 10.1093/jac/47.3.364